Intralobular breast carcinoma

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Invasive lobular carcinoma ILCsometimes called infiltrating lobular carcinoma, is the second most common type of breast cancer after invasive ductal carcinoma cancer that begins in the milk-carrying ducts and spreads beyond it. According to the American Cancer Society, more thanwomen in the United States find out they have invasive breast cancer each year. Lobular means that the cancer began in the milk-producing lobules, which empty out into the ducts that carry milk to the nipple.

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Breast cancers that have spread into surrounding breast tissue are known as invasive breast cancer. There are different kinds of invasive breast cancer. Some kinds are more common than others.

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Invasive lobular carcinoma is a type of breast cancer that begins in the milk-producing glands lobules of the breast. Invasive cancer means the cancer cells have broken out of the lobule where they began and have the potential to spread to the lymph nodes and other areas of the body. Invasive lobular carcinoma makes up a small portion of all breast cancers.

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Lobular carcinoma in situ LCIS is an incidental microscopic finding with characteristic cellular morphology and multifocal tissue patterns. The condition is a laboratory diagnosis and refers to unusual cells in the lobules of the breast. These lesions are preceded by atypical lobular hyperplasia and may follow a linear progression to invasive lobular carcinoma ILCwith specific genetic aberrations. Rarely, terminal ducts may be involved in lobular neoplasia, known as pagetoid spread.

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Invasive Lobular Carcinoma ILCalso known as infiltrating lobular carcinoma, is the second most common form of breast cancer diagnosed in the United States, representing percent of diagnosed invasive breast cancers. This type of cancer is more difficult to see on imaging because of the way the cells stream through the breast tissue. Invasive lobular carcinomas are usually larger than expected from the mammogram.

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Spotlight On Click here for issue 1, featuring our GI editor Dr. Raul Gonzalez.

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Lobular breast cancer, also called invasive lobular carcinoma ILCoccurs in the breast lobes or lobules. Lobules are the areas of the breast that produce milk. ILC is the second most common type of breast cancer. ILC affects about 10 percent of people with invasive breast cancer.

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An important part of diagnosing breast cancer is staging. Staging is the process of finding out how much cancer there is and where it is located. This information is used to plan cancer treatment and develop a prognosis.

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Infiltrating or invasive lobular carcinoma ILC of the breast is the second most common type of invasive breast cancer after invasive ductal carcinoma IDC "not otherwise specified" NOS. The mean age at presentation may be higher than for IDC. ILC is characterized microscopically by malignant monomorphic cells forming linear invasive columns that are loosely dispersed note: IDC is more typically a discrete mass. ILC frequently invades the normal tissues without invoking the vigorous desmoplastic response that usually accompanies IDC.


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